Genetic Drift Simulator

Enter your Starting Allele Frequency, Population Size, Number of Generations, Mutation Rate, and Number of Simulations into the Genetic Drift Simulator to calculate your Final Allele Frequency alongside Total Frequency Change, Fixation Events, and Loss Events — revealing just how much chance shapes the fate of a gene over time.

0.5
0.010.99

Initial frequency of allele A in the population (0.01 to 0.99)

Number of individuals in the population

How many generations to simulate

Probability of mutation per allele per generation

Run multiple simulations to see variation in outcomes

Results

Final Allele Frequency

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Total Frequency Change

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Fixation Events

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Loss Events

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Allele Frequency Over Generations

Results Table

Frequently Asked Questions

What is genetic drift and how does it affect populations?

Genetic drift is the random change in allele frequencies in a population over time due to sampling effects during reproduction. It's more pronounced in smaller populations and can lead to the loss or fixation of alleles regardless of their selective advantage.

How does population size affect genetic drift?

Smaller populations experience stronger genetic drift because random sampling has a larger proportional effect. In large populations, random changes tend to cancel out, while in small populations, chance events can dramatically alter allele frequencies.

What does allele fixation mean in population genetics?

Allele fixation occurs when an allele reaches a frequency of 1.0 (100%) in the population, meaning all individuals carry that allele. Once fixed, the allele cannot be lost except through mutation or migration.

How does mutation rate influence genetic drift simulations?

Mutation introduces new genetic variation and can counteract the loss of alleles due to drift. Higher mutation rates maintain more genetic diversity, while lower rates allow drift to more easily fix or eliminate alleles.

Why do multiple simulations show different outcomes?

Each simulation represents one possible evolutionary pathway under random genetic drift. The stochastic nature of drift means that identical starting conditions can lead to very different outcomes, demonstrating the unpredictable nature of evolution in finite populations.

What is the relationship between starting frequency and fixation probability?

In neutral evolution (no selection), the probability that an allele will become fixed equals its starting frequency. An allele starting at 0.3 frequency has a 30% chance of fixation, while one at 0.7 has a 70% chance.

How can I interpret the genetic drift simulation results?

Look at the trajectory of allele frequency over time and note whether it trends toward 0 (loss) or 1 (fixation). The variability between simulations shows the random nature of drift, while the overall patterns reveal underlying population genetic principles.

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