What is a meta-analysis and why is it used?
A meta-analysis is a statistical technique that combines the results of multiple independent studies addressing the same research question. By pooling data, it increases statistical power, resolves conflicts between studies, and produces a more precise overall estimate of the true effect size than any single study could provide. See also our Total Within-Cluster SSE — Cluster Analysis.
What is the difference between fixed-effect and random-effects models?
A fixed-effect model assumes all studies share one true underlying effect and that differences between study results are due only to sampling error. A random-effects model (typically DerSimonian-Laird) assumes the true effect varies across studies and models that between-study variance (τ²). Random-effects is generally preferred when studies come from different populations or settings.
What does I² mean in a meta-analysis?
I² quantifies the proportion of total variability in effect estimates due to true between-study heterogeneity rather than chance. Values of 25%, 50%, and 75% are commonly interpreted as low, moderate, and high heterogeneity, respectively. High I² suggests the studies may be measuring different things and a random-effects model is more appropriate.
What effect size types does this calculator support?
This calculator supports standardized mean differences (Cohen's d / Hedges' g), raw mean differences (MD), odds ratios (on the log scale), risk ratios (on the log scale), and correlation coefficients (r). Enter the appropriate pre-computed effect size and its standard error for each study.
How do I find the standard error for each study?
The standard error is typically reported in the study's results section or statistical tables. If only a confidence interval is reported, you can back-calculate SE as (upper CI − lower CI) / (2 × z*), where z* is the critical value for your chosen confidence level (e.g., 1.96 for 95%). Some effect-size calculators also compute SE from sample sizes and group statistics.
What is τ² (tau-squared) in random-effects meta-analysis?
τ² is the estimated variance of the true effect sizes across studies in a random-effects model. It quantifies how much the true effects differ from study to study. A τ² of 0 indicates no between-study variance (equivalent to a fixed-effect model), while larger values indicate greater heterogeneity.
How many studies do I need for a meta-analysis?
While there is no strict minimum, meta-analyses with fewer than 3–5 studies may produce unstable estimates, especially for heterogeneity statistics like I² and τ². More studies generally yield more reliable pooled estimates and more meaningful heterogeneity assessments. This calculator supports up to 6 studies; for larger datasets, specialized software such as R (metafor) or RevMan is recommended. You might also find our Cronbach's Alpha Calculator useful.