Creatinine Clearance Calculator

Creatinine clearance measures how well your kidneys filter creatinine from your blood. It's an important indicator of kidney function, helping doctors assess kidney health and determine appropriate medication dosing.

The Cockcroft-Gault formula, developed in 1973, estimates creatinine clearance using age, weight, gender, and serum creatinine levels. While historically important, it's now mainly used for research purposes rather than clinical diagnosis.

The Cockcroft-Gault formula is no longer recommended for clinical use because it hasn't been updated with standardized creatinine values and newer equations like CKD-EPI are more accurate for estimating kidney function.

Normal creatinine clearance is typically 90-120 mL/min for healthy adults. Values below 60 mL/min may indicate chronic kidney disease, while values below 15 mL/min suggest severe kidney dysfunction.

The Cockcroft-Gault formula multiplies the result by 0.85 for females because women typically have less muscle mass than men, resulting in lower baseline creatinine production.

No, this calculator should not be used for drug dosing or clinical decisions. For drug dosing, healthcare providers should use more current equations like CKD-EPI or consult with a pharmacist or nephrologist.

Creatinine levels can be affected by muscle mass, diet (especially meat consumption), certain medications, dehydration, and kidney function. Always consult a healthcare provider for interpretation of lab results.

Yes, the Cockcroft-Gault equation is still used in research settings and some drug studies for historical comparison. However, for clinical assessment of kidney function, newer equations are preferred.